Biophysical Assays for Drug Discovery
Advanced biophysical characterization of drug-target and protein-protein interactions, using ITC, SPR and BLI; measurements of affinity, thermodynamics and kinetics, determinations of stoichiometry and active concentration, characterization of ternary PROTAC complexes.
Bio-layer Interferometry // Surface Plasmon Resonance // Isothermal Titration Calorimetry
Quality Assessment of Proteins and Peptides
Concentration and Molar Mass Measurements
Secondary, Tertiary and Quaternary Structure Characterization
Oligomerization and Aggregation Assessment
Absorbance , Fluorescence and Circular Dichroism Spectrometry // Size Exclusion Chromatography with Static and Dynamic Light Scattering
Optical Characterization of Inorganic, Hybrid, and Soft Materials
UV-Vis/NIR Absorption and Reflectance Measurements
UV-Vis Fluorescence Measurements
Secondary Structure of Non-Protein Polymeric Materials and Peptide Amphiphiles Measurements
UV/Vis Spectrometry // Fluorescence Spectrometry
