Circular Dichroism Spectrophotometer

Our state-of-the-art Jasco J-815 CD instrument allows the simultaneous acquisition of fluorescence and CD data. Such experiments are particularly useful in assessing the extent to which protein unfolding and folding transitions are two-state in character.

Select Applications:

  • Protein conformational studies
  • Quantitative analysis of pharmaceuticals
  • Formulation studies
  • Protein folding studies
  • DNA/RNA interactions
  • Enzyme kinetics
  • Purity testing of optically active substances
  • Natural products chemistry

Accessories:

  • Two photomultiplier tubes (165-900 nm and 600-1100 nm)
  • Peltier sample holder (used with 1mm, 2mm, 5mm, or 10mm path length cuvettes) for thermal denaturation studies (4- 110 degrees Celsius)
  • Cylindrical cuvette holder with water jacketed cuvettes using water bath
  • Titrator for automated chemical denaturation or ligand-binding studies
  • Cut-on filters for the fluorescence detector
  • Spectra Manager (Experiment and Analysis) and CD-PRO interface

For more information about the instrument, please see here.

Location: Cook Hall, 4118

NU Core ID: Circular Dichroism Spec. J-815